Exercise and cancer: how physical activity lowers risk

Updated Six Habits Editorial Team
The short answerPhysical activity is linked to lower risk of many cancers. An analysis of data from 1.44 million people found that higher leisure-time activity was associated with lower risk of 13 of 26 cancer types. The review behind the U.S. Physical Activity Guidelines found strong evidence for seven cancers, and evidence that activity after diagnosis is linked to better survival for breast, colorectal and prostate cancer.

Key points

What the research shows

1.44 million people. Pooling 12 U.S. and European cohorts, researchers found that higher levels of leisure-time physical activity were linked to lower risk of 13 of 26 cancer types, including esophageal adenocarcinoma, liver, lung, kidney, stomach, endometrial, colon and breast cancer. Most associations held regardless of body weight (Moore et al., 2016).

U.S. guidelines review. The 2018 Physical Activity Guidelines Advisory Committee found strong evidence that physical activity lowers the risk of bladder, breast, colon, endometrial, esophageal, kidney and stomach cancer. It also found evidence that higher activity after diagnosis is linked to lower mortality in people with breast, colorectal and prostate cancer (McTiernan et al., 2019).

In practice

Frequently asked questions

How much activity lowers cancer risk?

Most benefits were seen at or above the guideline of 150 to 300 minutes of moderate activity a week, but any activity is better than none.

Is exercise safe during chemotherapy?

For most people, yes, with adjustments. The American College of Sports Medicine says exercise during and after treatment is generally safe and helps with fatigue and quality of life.

Sources

  1. Moore et al. (2016). Association of Leisure-Time Physical Activity With Risk of 26 Types of Cancer in 1.44 Million Adults. JAMA Internal Medicine 176(6):816. doi:10.1001/jamainternmed.2016.1548
  2. MCTIERNAN et al. (2019). Physical Activity in Cancer Prevention and Survival: A Systematic Review. Medicine & Science in Sports & Exercise 51(6):1252-1261. doi:10.1249/MSS.0000000000001937
  3. Bull et al. (2020). World Health Organization 2020 guidelines on physical activity and sedentary behaviour. British Journal of Sports Medicine 54(24):1451-1462. doi:10.1136/bjsports-2020-102955

Prepared according to our evidence methodology and the principles of lifestyle medicine. For education only; it does not replace advice from your doctor.

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