Which drugs are most harmful? What a UK expert analysis found

Updated Six Habits Editorial Team
The short answerIn a study by UK experts, 20 drugs were rated on 16 criteria of harm to users and to others. Counting harm to society, such as violence, crashes and family breakdown, alcohol ranked as the most harmful drug, ahead of heroin and crack cocaine. Legal does not mean safe.

Key points

What the study showed

In a multicriteria decision analysis published in The Lancet, members of the UK Independent Scientific Committee on Drugs scored 20 drugs on 16 criteria: 9 related to harm to the user (such as death, dependence and damage to health) and 7 to harm to others (such as crime, family breakdown and economic costs).

Overall, alcohol scored highest, followed by heroin and crack cocaine. Heroin, crack and methamphetamine were most harmful to users, while alcohol, heroin and crack were most harmful to others. Tobacco ranked sixth overall (Nutt et al., 2010).

The Global Burden of Disease study also found alcohol to be a leading risk factor for death and disability worldwide (GBD 2016 Alcohol Collaborators, 2018), and smoking costs more than a decade of life on average (Jha et al., 2013).

Limits

The ranking reflects expert judgment and UK conditions in 2010, before fentanyl transformed the U.S. overdose crisis.

Frequently asked questions

Does this mean heroin is safer than alcohol?

No. Heroin is extremely harmful to the individual. Alcohol ranks highest overall mainly because it is so widely used and harms others.

Would U.S. rankings be different?

Probably in detail, especially with fentanyl, but the main conclusions about alcohol and tobacco are likely similar.

Sources

  1. Nutt et al. (2010). Drug harms in the UK: a multicriteria decision analysis. The Lancet 376(9752):1558-1565. doi:10.1016/S0140-6736(10)61462-6
  2. Griswold et al. (2018). Alcohol use and burden for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet 392(10152):1015-1035. doi:10.1016/S0140-6736(18)31310-2
  3. Jha et al. (2013). 21st-Century Hazards of Smoking and Benefits of Cessation in the United States. New England Journal of Medicine 368(4):341-350. doi:10.1056/NEJMsa1211128

Prepared according to our evidence methodology and the principles of lifestyle medicine. For education only; it does not replace advice from your doctor.

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